Brumbies hosts the Reds on Saturday from 6.15am with a live broadcast on ESPN Play, and both teams confirmed their starting lineups.
Brumbies coach Dan McKellar will make a single change in the opening XV for the game against the Reds at GIO Stadium.
The fifth round match will feature an undefeated match at Super Rugby Australia and will also be the first time the Brumbies have worn an indigenous game jersey.
Darcy Swain returns after missing the 24-0 victory over the Western Force and will partner with Nick Frost for the first time on the second line.
For his part, Reds will have the return of Jordan Petaia who will make his expected return after recovering after suffering from his dislocated shoulder that he suffered in Buenos Aires five months ago, while Fotuaika also returns from a foot injury.
The inclusion of the duo, are two of the eight changes for the clash this weekend in the Australian capital.
Dane Zander will start as a pillar in place of Harry Hoopert who will be out for another four to five weeks due to injury. Angus Blyth takes his place on the second line with Lukhan Salakaia-Loto.
On the third line, Angus Scott-Young changes sides to make room for captain Liam Wright who will return to wearing jersey number seven.
There is only one change on the back line with Scott Malolua in his first game as a starter in Super Rugby Australia, as a scrum half.
BRUMBIES: 15 Tom Banks, 14 Solomone Kata, 13 Tevita Kuridrani, 12 Irae Simone, 11 Tom Wright, 10 Bayley Kuenzle, 9 Joe Powell, 8 Pete Samu, 7 Will Miller, 6 Rob Valetini, 5 Nick Frost, 4 Darcy Swain, 3 Allan Alaalatoa (c), 2 Folau Fainga’a, 1 Scott Sio
Substitutes: 16 Connal McInerney, 17 James Slipper, 18 Tom Ross, 19 Tom Cusack, 20 Lachlan McCaffrey, 21 Issak Fines, 22 Mack Hansen, 23 Andy Muirhead
REDS: 15 Jock Campbell, 14 Chris Feauai-Sautia, 13 Hunter Paisami, 12 Hamish Stewart, 11 Filipo Daugunu, 10 James O’Connor, 9 Scott Malolua, 8 Harry Wilson, 7 Liam Wright (c), 6 Angus Scott-Young, 5 Lukhan Salakaia-Loto, 4 Angus Blyth, 3 Taniela Tupou, 2 Brandon Paenga-Amosa, 1 Dane Zander
Substitutes: 16 Alex Mafi, 17 Feao Fotuaika, 18 Jack Straker, 19 Ryan Smith, 20 Fraser McReight, 21 Tate McDermott, 22 Bryce Hegarty, 23 Jordan Petaia
Place: GIO Stadium, Canberra
Referee: Nic Berry
Assistants: Jordan Way, Reuben Keane
TMO: Ian Smith