Serena Williams, first seeded in Lexington (Kentucky, from August 10 to 16) will debut against her compatriot Bernarda Pera while Venus will make her debut against Belarusian Victoria Azarenka. If the sisters succeed, they will meet in the second round.
Sloane Stephens, a 2017 US Open winner and seventh seeded, is on the same side of the picture as the Williams sisters. Stephens makes her debut against a qualifying player and in second she would face Roger or Doi.
On the other side of the picture, the presence of Vera Zvoraneva, former World No. 2, and Coco Gauff stand out.